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What kinesin does at roadblocks: the coordination mechanism for molecular walking
Competing models for the coordination of processive stepping in kinesin can be tested by introducing a roadblock to prevent lead head attachment. We used T93N, an irreversibly binding mutant monomer, as a roadblock, and measured the rates of nucleotide-induced detachment of kinesin monomers or dimer...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271674/ https://ncbi.nlm.nih.gov/pubmed/14685258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600042 |
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