In Vitro and In Vivo Activities of Posaconazole against Coccidioides immitis

Posaconazole (SCH 56592) was tested against 25 strains of Coccidioides immitis to determine their in vitro susceptibilities. The geometric mean 48-h MIC of posaconazole (POSA) was 0.5 μg/ml, the MIC range was 0.25 to 1 μg/ml, and the MIC at which 50% of the isolates tested are inhibited (MIC(50)) an...

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Bibliographic Details
Main Authors: González, Gloria M., Tijerina, Rolando, Najvar, Laura K., Bocanegra, Rosie, Rinaldi, Michael, Loebenberg, David, Graybill, John R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127157/
https://ncbi.nlm.nih.gov/pubmed/11959568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1352-1356.2002
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