In Vitro and In Vivo Activities of Posaconazole against Coccidioides immitis

Posaconazole (SCH 56592) was tested against 25 strains of Coccidioides immitis to determine their in vitro susceptibilities. The geometric mean 48-h MIC of posaconazole (POSA) was 0.5 μg/ml, the MIC range was 0.25 to 1 μg/ml, and the MIC at which 50% of the isolates tested are inhibited (MIC(50)) an...

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Bibliographische Detailangaben
Hauptverfasser: González, Gloria M., Tijerina, Rolando, Najvar, Laura K., Bocanegra, Rosie, Rinaldi, Michael, Loebenberg, David, Graybill, John R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127157/
https://ncbi.nlm.nih.gov/pubmed/11959568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1352-1356.2002
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