Curcumin Treatment Abrogates Endoplasmic Reticulum Retention and Aggregation-Induced Apoptosis Associated with Neuropathy-Causing Myelin Protein Zero–Truncating Mutants

Mutations in MPZ, the gene encoding myelin protein zero (MPZ), the major protein constituent of peripheral myelin, can cause the adult-onset, inherited neuropathy Charcot-Marie-Tooth disease, as well as the more severe, childhood-onset Dejerine-Sottas neuropathy and congenital hypomyelinating neurop...

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Главные авторы: Khajavi, Mehrdad , Inoue, Ken , Wiszniewski, Wojciech , Ohyama, Tomoko , Snipes, G. Jackson , Lupski, James R. 
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Human Genetics 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271391/
https://ncbi.nlm.nih.gov/pubmed/16252242
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