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Nonparametric Population Pharmacokinetic Analysis of Amikacin in Neonates, Infants, and Children

The therapeutic and toxic effects of amikacin are known to depend on its concentration in plasma, but the pharmacokinetics of this drug in neonates, infants, and children and the influences of clinical and biological variables have been only partially assessed. Therapeutic drug monitoring data colle...

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Main Authors: Tréluyer, J. M., Merlé, Y., Tonnelier, S., Rey, E., Pons, G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC127129/
https://ncbi.nlm.nih.gov/pubmed/11959572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1381-1387.2002
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