Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene

Exon 3 of the human apolipoprotein A-II (apoA-II) gene is efficiently included in the mRNA although its acceptor site is significantly weak because of a peculiar (GU)(16) tract instead of a canonical polypyrimidine tract within the intron 2/exon 3 junction. Our previous studies demonstrated that the...

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Bibliographic Details
Main Authors: Mercado, Pablo Arrisi, Ayala, Youhna M., Romano, Maurizio, Buratti, Emanuele, Baralle, Francisco E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1270946/
https://ncbi.nlm.nih.gov/pubmed/16254078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki897
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