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Protein–DNA binding specificity predictions with structural models
Protein–DNA interactions play a central role in transcriptional regulation and other biological processes. Investigating the mechanism of binding affinity and specificity in protein–DNA complexes is thus an important goal. Here we develop a simple physical energy function, which uses electrostatics,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1270944/ https://ncbi.nlm.nih.gov/pubmed/16246914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki875 |
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