Fourteen-Member Macrolides Suppress Interleukin-8 Production but Do Not Promote Apoptosis of Activated Neutrophils

A 14-member macrolide was found to inhibit interleukin-8 (IL-8) synthesis in lipopolysaccharide-stimulated neutrophils but did not accelerate apoptosis in activated neutrophils. These data suggest that 14-member macrolides achieve clinical efficacy for chronic airway diseases partly by suppressing I...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tsuchihashi, Yoshiko, Oishi, Kazunori, Yoshimine, Hiroyuki, Suzuki, Shoichi, Kumatori, Atsushi, Sunazuka, Toshiaki, Omura, Satoshi, Matsushima, Kouji, Nagatake, Tsuyoshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Biologic Response Modifiers
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11897597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.4.1101-1104.2002
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