Efficacy of TAK-457, a Novel Intravenous Triazole, against Invasive Pulmonary Aspergillosis in Neutropenic Mice

TAK-457 is an injectable prodrug of TAK-456, which is a novel oral triazole compound with potent antifungal activity. The in vivo efficacy of TAK-457 was evaluated in two models of invasive pulmonary aspergillosis with CDF(1) mice and CBA/J mice with transient neutropenia induced by cyclophosphamide...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hayashi, Ryogo, Kitamoto, Naomi, Iizawa, Yuji, Ichikawa, Takashi, Itoh, Katsumi, Kitazaki, Tomoyuki, Okonogi, Kenji
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.2.283-287.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!