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Bactericidal Activities of BMS-284756, a Novel Des-F(6)-Quinolone, against Staphylococcus aureus Strains with Topoisomerase Mutations

The antistaphylococcal activities of BMS-284756 (T-3811ME), levofloxacin, moxifloxacin, and ciprofloxacin were compared against wild-type and grlA and grlA/gyrA mutant strains of Staphylococcus aureus. BMS-284756 was the most active quinolone tested, with MICs and minimal bactericidal concentrations...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Lawrence, Laura E., Frosco, MaryBeth, Ryan, Brenda, Chaniewski, Susan, Yang, Hyekyung, Hooper, David C., Barrett, John F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751133/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.1.191-195.2002
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