HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors

Lignende værker

• Mutations That Confer Resistance to Template-Analog Inhibitors of Human Immunodeficiency Virus (HIV) Type 1 Reverse Transcriptase Lead to Severe Defects in HIV Replication
  af: Fisher, Timothy S., et al.
  Udgivet: (2002)
• Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by Template Analog Reverse Transcriptase Inhibitors Derived by SELEX (Systematic Evolution of Ligands by Exponential Enrichment)
  af: Joshi, Pheroze, et al.
  Udgivet: (2002)
• Interaction between Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Integrase Proteins
  af: Hehl, Eric A., et al.
  Udgivet: (2004)
• Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter
  af: Braun, Stephen E, et al.
  Udgivet: (2007)
• Standardized Comparison of the Relative Impacts of HIV-1 Reverse Transcriptase (RT) Mutations on Nucleoside RT Inhibitor Susceptibility
  af: Melikian, George L., et al.
  Udgivet: (2012)