Anthrax Lethal Toxin-Mediated Killing of Human and Murine Dendritic Cells Impairs the Adaptive Immune Response

Many pathogens have acquired strategies to combat the immune response. Bacillus anthracis interferes with host defenses by releasing anthrax lethal toxin (LT), which inactivates mitogen-activated protein kinase pathways, rendering dendritic cells (DCs) and T lymphocytes nonresponsive to immune stimu...

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Dettagli Bibliografici
Autori principali: Alileche, Abdelkrim, Serfass, Evan R, Muehlbauer, Stefan M, Porcelli, Steven A, Brojatsch, Jürgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266308/
https://ncbi.nlm.nih.gov/pubmed/16254597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0010019
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