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Anthrax Lethal Toxin-Mediated Killing of Human and Murine Dendritic Cells Impairs the Adaptive Immune Response

Many pathogens have acquired strategies to combat the immune response. Bacillus anthracis interferes with host defenses by releasing anthrax lethal toxin (LT), which inactivates mitogen-activated protein kinase pathways, rendering dendritic cells (DCs) and T lymphocytes nonresponsive to immune stimu...

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Main Authors: Alileche, Abdelkrim, Serfass, Evan R, Muehlbauer, Stefan M, Porcelli, Steven A, Brojatsch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266308/
https://ncbi.nlm.nih.gov/pubmed/16254597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0010019
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