Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig

Alcoholic liver disease is associated with abnormal hepatic methionine metabolism and folate deficiency. Because folate is integral to the methionine cycle, its deficiency could promote alcoholic liver disease by enhancing ethanol-induced perturbations of hepatic methionine metabolism and DNA damage...

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Detalhes bibliográficos
Main Authors: Halsted, Charles H., Villanueva, Jesus A., Devlin, Angela M., Niemelä, Onni, Parkkila, Seppo, Garrow, Timothy A., Wallock, Lynn M., Shigenaga, Mark K., Melnyk, Stepan, James, S. Jill
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126626/
https://ncbi.nlm.nih.gov/pubmed/12122204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112336399
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