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A Gain-of-Function Allele of cbp-1, the Caenorhabditis elegans Ortholog of the Mammalian CBP/p300 Gene, Causes an Increase in Histone Acetyltransferase Activity and Antagonism of Activated Ras

An RTK-Ras-mitogen-activated protein kinase (MAPK) signaling pathway plays a key role in vulval induction in Caenorhabditis elegans. We have previously carried out screens for suppressors of activated Ras to identify factors that play critical roles in the regulation of the pathway. ku258 was isolat...

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Hlavní autoři: Eastburn, Dennis J., Han, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265831/
https://ncbi.nlm.nih.gov/pubmed/16227593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9427-9434.2005
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