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Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells

Vertebrate genomes each encode hundreds of micro-RNAs (miRNAs), yet for few of these miRNAs is there empirical evidence as to which mRNA(s) they regulate. Here we report the identification of human lin-28 mRNA as a regulatory target of human miR-125b and its homolog miR-125a. Studies of miR-125b fun...

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Autors principals: Wu, Ligang, Belasco, Joel G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265813/
https://ncbi.nlm.nih.gov/pubmed/16227573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9198-9208.2005
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