Viral FLIP Enhances Wnt Signaling Downstream of Stabilized β-Catenin, Leading to Control of Cell Growth

Death receptor-mediated apoptosis is potently inhibited by viral FLIP (FLICE/caspase 8 inhibitory protein), which is composed of two tandemly repeated death effector domains (DEDs), through reduced activation of procaspase 8. Here, we show that equine herpesvirus 2-encoded viral FLIP E8 enhances Wnt...

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Detalhes bibliográficos
Main Authors: Nakagiri, Shiho, Murakami, Akira, Takada, Shinji, Akiyama, Tetsu, Yonehara, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265812/
https://ncbi.nlm.nih.gov/pubmed/16227577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9249-9258.2005
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