A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16

We describe a stable, multisubunit human histone acetyltransferase complex (hMSL) that contains homologs of the Drosophila dosage compensation proteins MOF, MSL1, MSL2, and MSL3. This complex shows strong specificity for histone H4 lysine 16 in chromatin in vitro, and RNA interference-mediated knock...

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Detalhes bibliográficos
Main Authors: Smith, Edwin R., Cayrou, Christelle, Huang, Rong, Lane, William S., Côté, Jacques, Lucchesi, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265810/
https://ncbi.nlm.nih.gov/pubmed/16227571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9175-9188.2005
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