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Synaptotagmin VII Is Targeted to Secretory Organelles in PC12 Cells, Where It Functions as a High-Affinity Calcium Sensor

Synaptotagmin (syt) I is thought to act as a Ca(2+) sensor that regulates neuronal exocytosis. Fifteen additional isoforms of syt have been identified, but their functions are less well understood. Here, we used PC12 cells to test the idea that different isoforms of syt impart cells with distinct me...

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Hlavní autoři: Wang, Ping, Chicka, Michael C., Bhalla, Akhil, Richards, David A., Chapman, Edwin R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265757/
https://ncbi.nlm.nih.gov/pubmed/16166648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8693-8702.2005
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