Single-Base-Pair Discrimination of Terminal Mismatches by Using Oligonucleotide Microarrays and Neural Network Analyses

The effects of single-base-pair near-terminal and terminal mismatches on the dissociation temperature (T(d)) and signal intensity of short DNA duplexes were determined by using oligonucleotide microarrays and neural network (NN) analyses. Two perfect-match probes and 29 probes having a single-base-p...

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Bibliografiske detaljer
Main Authors: Urakawa, Hidetoshi, Noble, Peter A., El Fantroussi, Said, Kelly, John J., Stahl, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC126557/
https://ncbi.nlm.nih.gov/pubmed/11772632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.1.235-244.2002
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