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Inhibition of purine phosphoribosyltransferases from Ehrlich ascites-tumour cells by purine nucleotides

1. The purine bases adenine, hypoxanthine and guanine were rapidly incorporated into the nucleotide fraction of Ehrlich ascites-tumour cells in vivo. 2. The reaction of 5′-phosphoribosyl pyrophosphate with adenine phosphoribosyltransferase from ascites-tumour cells (K(m) 6·5–11·9μm) was competitivel...

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Bibliographic Details
Main Author: Murray, A. W.
Format: Artigo
Language:Inglês
Published: 1966
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265200/
https://ncbi.nlm.nih.gov/pubmed/5969281
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