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In vitro assessments of the genetic stability of a live recombinant human adenovirus vaccine against rabies.

The genetic stability of a live human adenovirus 5: rabies glycoprotein recombinant vaccine has been assessed upon 20 serial passages in a permissive cell line of human origin. Restriction endonuclease analysis and the polymerase chain reaction were used to examine the integrity of the expression ca...

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Bibliographic Details
Main Authors: Lutze-Wallace, C, Sapp, T, Sidhu, M, Wandeler, A
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1263755/
https://ncbi.nlm.nih.gov/pubmed/7648530
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