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Approaches for genetic purity testing of live recombinant viral vaccines using a human adenovirus:rabies model.

A two part purity testing regimen for genetically engineered live viral vaccines is described using a human adenovirus 5: rabies glycoprotein gene recombinant as a model vaccine. Initially, restriction endonuclease analysis of the recombinant viral genome verified the integrity of the recombinant co...

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Detalhes bibliográficos
Main Authors: Lutze-Wallace, C, Sapp, T, Nadin-Davis, S A, Wandeler, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1263569/
https://ncbi.nlm.nih.gov/pubmed/1477804
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