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Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication
A series of amino acid substitutions (M239F, M239G, P240F, V241G) were placed in the p10-CA protease cleavage site (VVAM*PVVI) to change the rate of cleavage of the junction. The effects of these substitutions on p10-CA cleavage by RSV PR were confirmed by measuring the kinetics of cleavage of model...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1262776/ https://ncbi.nlm.nih.gov/pubmed/16188035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-58 |
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