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A Single-Cycle Vaccine Vector Based on Vesicular Stomatitis Virus Can Induce Immune Responses Comparable to Those Generated by a Replication-Competent Vector

Live attenuated vaccine vectors based on recombinant vesicular stomatitis virus (VSV) are effective in several viral disease models. In this study, we asked if a VSV vector capable of only a single cycle of replication might be an effective alternative to replication-competent VSV vectors. We compar...

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Autori principali: Publicover, Jean, Ramsburg, Elizabeth, Rose, John K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262593/
https://ncbi.nlm.nih.gov/pubmed/16227246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13231-13238.2005
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