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Prophylactic Alpha Interferon Treatment Increases the Therapeutic Index of Oncolytic Vesicular Stomatitis Virus Virotherapy for Advanced Hepatocellular Carcinoma in Immune-Competent Rats
Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with intrinsic oncolytic specificity due to substantially attenuated antiviral responses in many tumors. We have recently reported that recombinant VSV vector can be used as an effective oncolytic agent to safely treat multifocal hepato...
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Glavni autori: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Microbiology
2005
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1262571/ https://ncbi.nlm.nih.gov/pubmed/16227290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13705-13713.2005 |
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