Complex Determinants in Human Immunodeficiency Virus Type 1 Envelope gp120 Mediate CXCR4-Dependent Infection of Macrophages

Host cell range, or tropism, combined with coreceptor usage defines viral phenotypes as macrophage tropic using CCR5 (M-R5), T-cell-line tropic using CXCR4 (T-X4), or dually lymphocyte and macrophage tropic using CXCR4 alone or in combination with CCR5 (D-X4 or D-R5X4). Although envelope gp120 V3 is...

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Bibliografiske detaljer
Main Authors: Ghaffari, Guity, Tuttle, Daniel L., Briggs, Daniel, Burkhardt, Brant R., Bhatt, Deepa, Andiman, Warren A., Sleasman, John W., Goodenow, Maureen M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262568/
https://ncbi.nlm.nih.gov/pubmed/16227248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13250-13261.2005
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