Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration

BACKGROUND: lnterleukin-2 (IL-2) has direct pluripotent effects on cells with immune and inflammatory function. Which of these effects has a critical role in mediating tumor regression remains enigmatic. In this study, we compared early changes in transcriptional profiles of circulating mononuclear...

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Main Authors: Panelli, Monica C, Wang, Ena, Phan, Giao, Puhlmann, Markus, Miller, Lance, Ohnmacht, Galen A, Klein, Harvey G, Marincola, Francesco M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2002
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC126240/
https://ncbi.nlm.nih.gov/pubmed/12184809
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