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Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1

XRCC1 protein is required for the repair of DNA single-strand breaks and genetic stability, and is essential for viability in mammals. XRCC1 functions as a scaffold protein by interacting and modulating polypeptide components of the single-strand break repair machinery, including AP endonuclease-1,...

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Publicat a:EMBO J
Autors principals: Iftner, Thomas, Elbel, Michaela, Schopp, Betti, Hiller, Thomas, Loizou, Joanna I., Caldecott, Keith W., Stubenrauch, Frank
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf443
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