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Acid-induced movements in the glycoprotein shell of an alphavirus turn the spikes into membrane fusion mode

In the icosahedral (T = 4) Semliki Forest virus, the envelope protomers, i.e. E1–E2 heterodimers, make one-to-one interactions with capsid proteins below the viral lipid bilayer, transverse the membrane and form an external glycoprotein shell with projections. The shell is organized by protomer doma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Haag, Lars, Garoff, Henrik, Xing, Li, Hammar, Lena, Kan, Sin-Tau, Cheng, R.Holland
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf442
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