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Acid-induced movements in the glycoprotein shell of an alphavirus turn the spikes into membrane fusion mode

In the icosahedral (T = 4) Semliki Forest virus, the envelope protomers, i.e. E1–E2 heterodimers, make one-to-one interactions with capsid proteins below the viral lipid bilayer, transverse the membrane and form an external glycoprotein shell with projections. The shell is organized by protomer doma...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Haag, Lars, Garoff, Henrik, Xing, Li, Hammar, Lena, Kan, Sin-Tau, Cheng, R.Holland
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf442
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