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Cis control of gene expression in E.coli by ribosome queuing at an inefficient translational stop signal

An UGA stop codon context which is inefficient because of the 3′-flanking context and the last two amino acids in the gene protein product has a negative effect on gene expression, as shown using a model protein A′ gene. This is particularly true at low mRNA levels, corresponding to a high intracell...

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Bibliografiska uppgifter
Huvudupphovsmän: Jin, Haining, Björnsson, Asgeir, Isaksson, Leif A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC126163/
https://ncbi.nlm.nih.gov/pubmed/12169638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf424
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