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Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets

Hepatitis C virus (HCV) is the major causative pathogen associated with liver cirrhosis and hepatocellular carcinoma. The virus has a positive-sense RNA genome encoding a single polyprotein with the virion components located in the N-terminal portion. During biosynthesis of the polyprotein, an inter...

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Autores principales: McLauchlan, John, Lemberg, Marius K., Hope, Graham, Martoglio, Bruno
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC126158/
https://ncbi.nlm.nih.gov/pubmed/12145199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf414
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