Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets

Hepatitis C virus (HCV) is the major causative pathogen associated with liver cirrhosis and hepatocellular carcinoma. The virus has a positive-sense RNA genome encoding a single polyprotein with the virion components located in the N-terminal portion. During biosynthesis of the polyprotein, an inter...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	McLauchlan, John, Lemberg, Marius K., Hope, Graham, Martoglio, Bruno
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12145199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf414
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