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Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD

Modular organization of proteins has been postulated as a widely used strategy for protein evolution. The multidomain transmembrane protein DsbD catalyzes the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli. Most bacterial species do not have DsbD, but instead their gen...

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Bibliographic Details
Main Authors: Katzen, Federico, Deshmukh, Meenal, Daldal, Fevzi, Beckwith, Jon
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC126151/
https://ncbi.nlm.nih.gov/pubmed/12145197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf405
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