Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD

Modular organization of proteins has been postulated as a widely used strategy for protein evolution. The multidomain transmembrane protein DsbD catalyzes the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli. Most bacterial species do not have DsbD, but instead their gen...

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Publié dans:	EMBO J
Auteurs principaux:	Katzen, Federico, Deshmukh, Meenal, Daldal, Fevzi, Beckwith, Jon
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12145197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf405
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