Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme

T4 polynucleotide kinase (Pnk), in addition to being an invaluable research tool, exemplifies a family of bifunctional enzymes with 5′-kinase and 3′-phosphatase activities that play key roles in RNA and DNA repair. T4 Pnk is a homotetramer composed of a C-terminal phosphatase domain and an N-termina...

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Publié dans:	EMBO J
Auteurs principaux:	Wang, Li Kai, Lima, Christopher D., Shuman, Stewart
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12110598/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf397
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