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G(1)/S CDK is inhibited to restrain mitotic onset when DNA replication is blocked in fission yeast

Cyclin-dependent kinase (CDK) Tyr15 phosphorylation plays a major role in regulating G(2)/M CDKs, but the role of this phosphorylation in regulating G(1)/S CDKs is less clear. We have studied the regulation and function of Cdc2-Tyr15 phosphorylation in the fission yeast Schizosaccharomyces pombe G(1...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Zarzov, Patrick, Decottignies, Anabelle, Baldacci, Giuseppe, Nurse, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf346
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