The DnaC helicase loader is a dual ATP/ADP switch protein

Helicases are transferred to replication origins by helicase loading factors. The Escherichia coli DnaC and eukaryotic Cdc6/18 helicase loaders contain ATP sites and are both members of the AAA+ family. One might expect that ATP is required for helicase loading; however, this study on DnaC illustrat...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Davey, Megan J., Fang, Linhua, McInerney, Peter, Georgescu, Roxana E., O’Donnell, Mike
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf308
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