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The DnaC helicase loader is a dual ATP/ADP switch protein

Helicases are transferred to replication origins by helicase loading factors. The Escherichia coli DnaC and eukaryotic Cdc6/18 helicase loaders contain ATP sites and are both members of the AAA+ family. One might expect that ATP is required for helicase loading; however, this study on DnaC illustrat...

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Publicat a:EMBO J
Autors principals: Davey, Megan J., Fang, Linhua, McInerney, Peter, Georgescu, Roxana E., O’Donnell, Mike
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065427/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf308
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