The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria
Ssc1, a molecular chaperone of the Hsp70 family, drives preprotein import into the mitochondrial matrix by a specific interaction with the translocase component Tim44. Two other mitochondrial Hsp70s, Ssc3 (Ecm10) and Ssq1, show high sequence homology to Ssc1 but fail to replace Ssc1 in vivo, possibl...
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| Publicado en: | EMBO J |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.11.2626 |
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