The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria
Ssc1, a molecular chaperone of the Hsp70 family, drives preprotein import into the mitochondrial matrix by a specific interaction with the translocase component Tim44. Two other mitochondrial Hsp70s, Ssc3 (Ecm10) and Ssq1, show high sequence homology to Ssc1 but fail to replace Ssc1 in vivo, possibl...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.11.2626 |
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