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Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70

The Ku70/80 heterodimer is a critical component of the non-homologous end-joining (NHEJ) pathway and of the telomere cap in yeast and mammals. We report the molecular characterization of the KU70 and KU80 genes in Arabidopsis and describe the consequences of a Ku70 deficiency. Arabidopsis KU70/80 ge...

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Udgivet i:EMBO J
Principais autores: Riha, Karel, Watson, J.Matthew, Parkey, Jeffrey, Shippen, Dorothy E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.11.2819
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