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A new mode for heme-heme interactions in hemoglobin associated with distal perturbations.

The distal side of the heme pocket, known to regulate ligand affinity, is shown to be directly involved in subunit interactions. Valency hybrids with oxygen or carbon monoxide bound to the reduced chain are used to model R-state hemoglobin with different distal perturbations. Electron paramagnetic r...

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Dettagli Bibliografici
Autori principali: Levy, A, Sharma, V S, Zhang, L, Rifkind, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1260292/
https://ncbi.nlm.nih.gov/pubmed/1324020
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