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The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules
The oxidoreductase ERp57 is an integral component of the peptide loading complex of major histocompatibility complex (MHC) class I molecules, formed during their chaperone-assisted assembly in the endoplasmic reticulum. Misfolded MHC class I molecules or those denied suitable peptides are retrotrans...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126025/ https://ncbi.nlm.nih.gov/pubmed/12032078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2655 |
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