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Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

Cell cycle progression in eukaryotes is mediated by phosphorylation of protein substrates by the cyclin-dependent kinases (CDKs). We screened a cDNA library by solid-phase phosphorylation and isolated hHR6A as a CDK2 substrate. hHR6A is the human homologue of the product of the Saccharomyces cerevis...

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Autori principali: Sarcevic, Boris, Mawson, Amanda, Baker, Rohan T., Sutherland, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125963/
https://ncbi.nlm.nih.gov/pubmed/11953320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.8.2009
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