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Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport
The Disabled-2 (Dab2) gene has been proposed to act as a tumor suppressor. Cell culture studies have implicated Dab2 in signal transduction by mitogens, TGFβ and endocytosis of lipoprotein receptors. To identify in vivo functions of Dab2, targeted mutations were made in the mouse. In the absence of...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125955/ https://ncbi.nlm.nih.gov/pubmed/11927540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1555 |
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