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Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport

The Disabled-2 (Dab2) gene has been proposed to act as a tumor suppressor. Cell culture studies have implicated Dab2 in signal transduction by mitogens, TGFβ and endocytosis of lipoprotein receptors. To identify in vivo functions of Dab2, targeted mutations were made in the mouse. In the absence of...

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Bibliografski detalji
Glavni autori: Morris, Shelli M., Tallquist, Michelle D., Rock, Charles O., Cooper, Jonathan A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125955/
https://ncbi.nlm.nih.gov/pubmed/11927540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1555
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