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Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis

Thioredoxin-2 (Trx-2) is a mitochondria-specific member of the thioredoxin superfamily. Mitochondria have a crucial role in the signal transduction for apoptosis. To investigate the biological significance of Trx-2, we cloned chicken TRX-2 cDNA and generated clones of the conditional Trx-2-deficient...

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Udgivet i:EMBO J
Principais autores: Tanaka, Toru, Hosoi, Fumihito, Yamaguchi-Iwai, Yuko, Nakamura, Hajime, Masutani, Hiroshi, Ueda, Shugo, Nishiyama, Akira, Takeda, Shunichi, Wada, Hiromi, Spyrou, Giannis, Yodoi, Junji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1695
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