Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis

Thioredoxin-2 (Trx-2) is a mitochondria-specific member of the thioredoxin superfamily. Mitochondria have a crucial role in the signal transduction for apoptosis. To investigate the biological significance of Trx-2, we cloned chicken TRX-2 cDNA and generated clones of the conditional Trx-2-deficient...

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Detalhes bibliográficos
Main Authors: Tanaka, Toru, Hosoi, Fumihito, Yamaguchi-Iwai, Yuko, Nakamura, Hajime, Masutani, Hiroshi, Ueda, Shugo, Nishiyama, Akira, Takeda, Shunichi, Wada, Hiromi, Spyrou, Giannis, Yodoi, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125951/
https://ncbi.nlm.nih.gov/pubmed/11927553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1695
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